SELECTED PUBLICATIONS

2025


Original Investigation

Nature Communications (April 2025)

A host-pathogen metabolic synchrony that facilitates disease tolerance

Ying-Tsun Chen, Gaurav Kumar Lohia, Samantha Chen, Zihua Liu, Tania Wong Fok Lung, Chu Wang, Sebastián A. Riquelme

[Nature] [PubMed]

Literature Review

Frontiers in Immunology (April 2025)

Influence of cell bioenergetics on host-pathogen interaction in the lung

Gaurav Kumar Lohia, Sebastián A. Riquelme

[Frontiers] [PubMed]

Literature Review

Current Opinion in Microbiology (April 2025)

Pathogen adaptation to lung metabolites

Gaurav Kumar Lohia, Sebastián A. Riquelme

[ScienceDirect] [PubMed]

2024


Literature Review

Journal of Innate Immunity (February 2024)

Immunometabolic regulation of bacterial infection, biofilms, and antibiotic susceptibility

Ying-Tsun Chen, Gaurav Kumar Lohia, Samantha Chen, Sebastián A. Riquelme

[Krager] [PubMed]

2023


Original Investigation

Cell Metabolism (October 2023)

Ketogenesis promotes tolerance to Pseudomonas aeruginosa pulmonary infection

Kira L. Tomlinson, Ying-Tsun Chen, Alex Junker, AndreaCarola Urso, Tania Wong Fok Lung, Danielle Ahn, Casey E. Hofstaedter, Swikrity U. Baskota, Robert K. Ernst, Alice Prince, Sebastián A. Riquelme

[Cell] [PubMed]

2022


Literature Review

Clinics in Chest Medicine (December 2022)

The Impact of Highly Effective Modulator Therapy on Cystic Fibrosis Microbiology and Inflammation

Lindsay J. Caverly, Sebastián A. Riquelme, Katherine B. Hisert

[Clinics in Chest Medicine] [PubMed]

2021


Original Investigation

Nature Communications (March 2021)

Staphylococcus aureus induces an itaconate-dominated immunometabolic response that drives biofilm formation

Kira L. Tomlinson, Tania Wong Fok Lung, Felix Dach, Medini K. Annavajhala, Stanislaw J. Gabryszewski, Ryan A. Groves, Marija Drikic, Nancy J. Francoeur, Shwetha H. Sridhar, Melissa L. Smith, Sara Khanal, Clemente J. Britto, Robert Sebra, Ian Lewis, Anne-Catrin Uhlemann, Barbara C. Kahl, Alice S. Prince, Sebastián A. Riquelme

[Nature] [PubMed]

2020


Original Investigation

Cell Metabolism (June 2020)

Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation

Sebastián A. Riquelme, Kalle Liimatta, Tania Wong Fok Lung, Blanche Fields, Danielle Ahn, David Chen, Carmen Lozano, Yolanda Sáenz, Anne-Catrin Uhlemann, Barbara C. Kahl, Clemente J. Britto, Emily DiMango, Alice Prince

[Cell] [PubMed]

2019


Original Investigation

Science Translational Medicine (July 2019)

CFTR-PTEN–dependent mitochondrial metabolic dysfunction promotes Pseudomonas aeruginosa airway infection

Sebastián A. Riquelme, Carmen Lozano, Ahmed M. Moustafa, Kalle Liimatta, Kira L. Tomlinson, Clemente Britto, Sara Khanal, Simren K. Gill, Apurva Narechania, Jose M. Azcona-Gutiérrez, Emily DiMango, Yolanda Saénz, Paul Planet, Alice Prince

[Science] [PubMed]

2017


Original Investigation

Immunity (December 2017)

Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity

Sebastián A. Riquelme, Benjamin D. Hopkins, Andrew L. Wolfe, Emily DiMango, Kipyegon Kitur, Ramon Parsons, Alice Prince

[Cell] [PubMed]